White Blood Cell (WBC) Test Reference Table – FOR PUBLIC REFERENCE 

(Normal Reference Values in Healthy Adults) 

Lymphocyte Population Analysis (Flow Cytometry) – FOR HEALTHCARE PROFESSIONALS 

(Normal Reference Values in Healthy Adults) 

Common causes of Lymphocyte increase and decrease 

An increase or decrease in the blood lymphocyte count is a sign that the body's immune function may be disordered, weakened, or has lost the function of one or more components of the immune system. This results in reduced efficacy of immune responses and a diminished ability of the body to protect itself against harmful factors.

• Causes of Lymphocyte Increase (Lymphocytosis): A high lymphocyte count is often a sign that the immune system is working to fight off pathogens or is caused by other medical conditions.

• Causes of Lymphocyte Decrease (Lymphopenia): A low lymphocyte count is often primary (due to genetics) or secondary, caused by related factors including: the neonatal period, malnutrition, autoimmune diseases, metabolic endocrine disorders, some cancers, viral hepatitis, infectious diseases, infections, surgery and trauma, some medical treatments, environmental factors, etc.

Malnutrition is the most common reason the body fails to produce sufficient lymphocytes, which can include deficiencies in vitamins and minerals such as vitamin B12, folic acid, and zinc. The body's lymphocyte count also gradually declines with age due to natural aging (senescence).

Understanding the causes of lymphocyte increase/decrease highlights the importance of a healthy lifestyle in supporting the overall immune system, especially during recovery or health maintenance alongside specialized treatment protocols.

Enhancing Lymphocyte Immunity 

Help support your immune system so your Lymphocytes remain robust with these healthy lifestyle habits:

• Smart Nutrition & Gut Health: Eat a varied diet rich in green vegetables, fruits, whole foods, and fiber. Emphasize fermented foods (like yogurt, kimchi) to strengthen the gut microbiome – the "foundation" of immunity.

• Sufficient Sleep & Exercise: Get 7-9 hours of sleep per night for Lymphocytes to rest. Light exercise helps Lymphocytes patrol effectively. Maintaining a healthy weight is also key to immunity.

• Stress Management: Stress is the "enemy" that weakens the immune system. Meditation, yoga, deep breathing, or making time for hobbies helps maintain an optimistic spirit.

• Avoid Toxins & Practice Hygiene: Limit tobacco, alcohol, pollutants, and harmful chemicals. Wash hands regularly and maintain a clean living environment to reduce the burden on the immune system.

• Considered Supplementation: If necessary, consult your doctor about supplementing with Vitamin D, Zinc, or C, but never overuse them.

The Immune cell lineages

Immune cells originate from hematopoietic stem cells in the bone marrow, forming the body's complex immune system. This system has evolved over millions of years with life itself, self-regulating its function based on your unique health history, living environment, and even age, and is divided into two main lineages:

• The Myeloid Lineage: Includes cells such as monocytes – precursors to macrophages, dendritic cells, and granulocytes (comprising neutrophils, eosinophils, and basophils).

• The Lymphoid Lineage: Includes B lymphocytes (B cells): Create antibodies to attack viruses, bacteria, and other infectious agents. Natural Killer (NK) cells: Serve as the first line of defense against pathogens. T lymphocytes (T cells): Control the body's immune response, directly attacking and destroying infected cells and tumors.